CMR substances are known or probable to be carcinogenic (cancer-causing in humans/animals), mutagenic (causing DNA mutations resulting in disease), and reprotoxic (affecting fertility, as well as cause developmental toxicity in the offspring). We do not use any materials in our formulations that are known toxins. However, some naturally derived components (such as terpenes) of ingredients may be listed on CMR statements and SDS documentation. These components are not added to the formula but rather exist as a chemical constituent of the materials used (which includes plant-based ingredients). Please let us know if you have any specific questions about CMRs and/or our formulations.